In recent times, tnf alpha gene has become increasingly relevant in various contexts. TNF Gene - GeneCards | TNFA Protein | TNFA Antibody. This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Complete information for TNFAIP3 gene (Protein Coding), TNF Alpha Induced Protein 3, including: function, proteins, disorders, pathways, orthologs, and expression.
TNFAIP1 Gene - GeneCards | BACD2 Protein | BACD2 Antibody. TNFAIP6 Gene - GeneCards | TSG6 Protein | TSG6 Antibody. The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes.
The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors.
TNFRSF1B Gene - GeneCards | TNR1B Protein | TNR1B Antibody. TNFAIP8L1 Gene - GeneCards | TP8L1 Protein | TP8L1 Antibody.
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